David Northway, public information officer for the Tallahassee Police Department, told ABC News two people were shot outside the store in the city at about 12:30 p.m.
They suffered “non-life threatening injuries.”
The Associated Press reported that it was not immediately known if the incident was related to Black Friday shopping, which kicks off the first day of the holiday shopping season.
"I don't think that it had anything to do with merchandise," said Kollet Probst, 30, according to USA Today.
"It was so odd and unprovoked that it just doesn't seem like it was a Black Friday mob."
USA Today said the victims were a man and a woman, but further details were not yet available.
It wasn't the only violent incident on Black Friday, which comes a day after Thanksgiving.
The San Antonio Express News reported that a man pulled a gun on another who punched him in the face at a Sears department store on Thursday.