The Associated Press reported that Scott, 68, had committed suicide by jumping from the Vincent Thomas Bridge spanning San Pedro and Terminal Island in Los Angeles about 12:30 p.m. on Sunday local time.
Los Angeles police Lt. Tim Nordquist said several people called 911 to report that someone had jumped from the Vincent Thomas Bridge, the AP reported.
The Los Angeles Times reported that investigators later found a suicide note in Scott’s office.
According to Forbes, Scott’s Toyota Prius parked on the bridge contained information leading to the discovery of the note.
Meanwhile, Scott's spokesman, Simon Halls, said in a statement: "I can confirm that Tony Scott has passed away. The family asks that their privacy is respected at this time."
The LA Times published a retrospective piece listing the highlights of Scott's filmography, which along with 1986's smash hit "Top Gun" included "Beverly Hills Cop II," "Days of Thunder," "Crimson Tide," "The Hunger," "Enemy of the State," "Spy Game," "True Romance," "Man on Fire," "Deja Vu," and "Unstoppable."
As well as directing, he served as producer or executive producer on many movies, including this summer’s "Prometheus" directed by his older brother.
His work drew such A-listed actors as Tom Cruise, Denzel Washington, Gene Hackman, Robert Redford, Sigourney Weaver and Will Smith, Forbes wrote, while his films were distributed by Disney or Viacom’s Paramount Pictures.